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Calendar of Events

Date Event Name
May 26 - 28, 2013 DDI Marbach Castle Conference

Genetically-defined Human Liver Microsomes

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Genetically-defined human liver microsomes are an in vitro test system used to investigate the influence that allelic variance of drug metabolizing enzymes might have on the safety and efficacy of new molecular entities.

XenoTech offers genetically-defined human liver microsomes from the following polymorphically expressed enzymes.

View available lot and characterization information here!

Products

Product #NameAmount
H2C19.HACYP2C19 High Activity (*1/*1)0.5 mL at 20 mg/mL
H2C19.MACYP2C19 Moderate Activity (*1/*2, *1/*3, *1/*4, *1/*5)0.5 mL at 20 mg/mL
H2C19.NACYP2C19 No Activity (*2/*2, *2/*3, etc.)0.5 mL at 20 mg/mL
H2C9.HACYP2C9 High Activity (*1/*1)0.5 mL at 20 mg/mL
H2C9.MACYP2C9 Moderate Activity (*1/*2, *1/*3, *1/*5, *2/*2, *2/*3)0.5 mL at 20 mg/mL
H2D6.HACYP2D6 High Activity (Activity score = 3)0.5 mL at 20 mg/mL
H2D6.MACYP2D6 Moderate Activity (Activity score = 0.5-2.5)0.5 mL at 20 mg/mL
H2D6.NACYP2D6 No Activity (Activity score = 0)0.5 mL at 20 mg/mL
H3A5.HACYP3A5 High Activity (*1/*1)0.5 mL at 20 mg/mL
H3A5.MACYP3A5 Moderate Activity (*1/*3)0.5 mL at 20 mg/mL
H3A5.NACYP3A5 No Activity (*3/*3)0.5 mL at 20 mg/mL
HU1A1.HAUGT1A1 High Activity (*1/*1)0.5mL at 20mg/mL
HU1A1.MAUGT1A1 Moderate Activity (*1/*28)0.5mL at 20mg/mL
HU1A1.NAUGT1A1 No Activity (*28/*28)0.5mL at 20mg/mL
HU1A9.HAUGT1A9 High Activity (*1/*1)0.5 mL at 20 mg/mL
HU1A9.MAUGT1A9 Moderate Activity (*1/*3)0.5 mL at 20 mg/mL
HU1A9.NAUGT1A9 No Activity (*3/*3)0.5 mL at 20 mg/mL